Bortezomib-related neuropathy may mask CNS relapse in multiple myeloma: A call for diligence
نویسندگان
چکیده
منابع مشابه
Bortezomib-related neuropathy may mask CNS relapse in multiple myeloma: A call for diligence
BACKGROUND Neuropathy is a common adverse effect of bortezomib. Isolated central nervous system (CNS) relapse in MM remains exceedingly rare and carries a dismal prognosis. We present an unusual case of bortezomib related neuropathy masking a CNS relapse of MM. CASE PRESENTATION A 57-year-old female was diagnosed with standard-risk MM with clinical and cytogenetic features not typically assoc...
متن کاملBortezomib-induced painful neuropathy in patients with multiple myeloma
Neurotoxicity towards the peripheral nervous system which appears clinically in the form of painful neuropathy is an essential dose-limiting factor during the treatment of multiple myeloma. In this review article different forms of this painful neuropathy are presented together with currently available diagnostic tools which are usually applied to confirm the diagnosis. Also, the most often use...
متن کاملBortezomib-induced peripheral neuropathy in patients with multiple myeloma.
Bortezomib-induced peripheral neuropathy (BIPN) often is difficult to manage or reverse once it occurs. Treatment usually involves dose-reduction, interruption, or cessation of therapy, as no other interventions have been proven effective. Oncology nurses must be vigilant and recognize BIPN early to prevent patients from experiencing symptoms and complications that may interfere with their qual...
متن کامل[Bortezomib-induced peripheral neuropathy in multiple myeloma patients].
OBJECTIVE To describe the side effects of bortezomib in treatment of multiple myeloma (MM), especially the incidence of peripheral neuropathy (PN). METHODS Information of 107 patients with MM who were treated with bortezomib in the First Affiliated Hospital of Zhejiang University from 2009 to 2014, were collected and analyzed retrospectively, to analyze the occurrence of adverse events during...
متن کاملElectroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy in multiple myeloma: a feasibility study
BACKGROUND This single-arm study evaluated feasibility, safety, and initial efficacy of electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy (PN) in cancer patients with multiple myeloma. METHODS Patients with neuropathy ≥ grade 2 received 20 acupuncture treatments over 9 weeks. RESULTS For the 19 evaluable patients, Functional Assessment of Cancer Therapy/Gynecologic...
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ژورنال
عنوان ژورنال: Cancer Biology & Therapy
سال: 2016
ISSN: 1538-4047,1555-8576
DOI: 10.1080/15384047.2016.1178427